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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6663dce3200c07830b242a631d6f823e515f8a22f8f3fa4aba7f56821c8edd50' 
  AND token = 'htPpnuJeulKU1SExW8j1Qeekn/D8QbbLG7qk0Qs4884=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}