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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46359b77a6087b26629406641408dfb614498f7c04a1a896ae7f79ebfef7e937' 
  AND token = 'jW6Z1/uSzV6o5bFNyRR2fCxRHer4ejWf+2oOwC20kOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}