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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d3e8a2c52da732da902684a3d1763828dc05adf0d163295405f288c76938cc' 
  AND token = 'a3H1D94QlebPPs6lDsxshbbfaHtXMB5BMOLLHlUaIxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}