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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4b8f3367b2149132b5bb2f87e291962cb60d354eb335eb415b3815ed051a7e' 
  AND token = 'cQyR1LVpAwyTUxsC3px2oZwO2+22U3jjPS2SboGulws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}