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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd9452f0201a89aeb3ce3ac749a49c12471a16158fd98a4985e77d18004ed26' 
  AND token = 'JJ2LywevVEjlnujE43MHhJzB5rd7j4PevW3/RHPSUAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}