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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37be1d7603012f2cff7cd79cf74bdaee230ec4c669d1cfda91f416345f6d6c46' 
  AND token = 'qbHztaTWb246t9RmD8IoOqlyygmaFRiqJJt0+9raybA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}