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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647cd654625232108e0e157c90eb87e122ffa378ecd689c428e34d0cb4407bc6' 
  AND token = 'iDZGdG78f2KSvhDix5GD8jxoJWMJGuABd6gWFEV4TeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}