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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6d544a1266623d4b23c462adab2b8150bb9982681f2d8cac3208789b948b73' 
  AND token = 'mU4XcxDrRY+dGvopfovEvJM7pECCWFeaDzJF1OKn3mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}