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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cd5a354a9cf05f278baf13cd4f5abf0f5813b43151932ec1fef4284c32b383' 
  AND token = '12vwUFWekA7fYEjrSCNdSzoChomqM0zx+X3qmmI8mJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}