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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd809d3492b309928bb43cb6395456582fc43457a5a6f4c1f9c2e47abca1578f6' 
  AND token = 'YQQMa/QTv4KX+ikdE9UUlmmb7xpBV4r2GssFecJkuf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}