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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca25b599a37b7a8c2ac789c9180efb1c47ef5d4b32e21f53eda883615058baf' 
  AND token = 'hOOdC9No2p7eJ4wiWpHoXRQF9Quzh9OmCThXpJzpJhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}