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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b501d8597bce62b81a9136309b7296dca8bea1486850c2d17be1c50de36b47' 
  AND token = 'Hb+qQ5KGe/VKsrmZ1OjsCXzo10urn4Tb0fHtUZCksig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}