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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778deeb8ac1c90d4c85b77908032e26582c1eb997c5dcf8a352819117d81156e' 
  AND token = 'avXWqwrNinKC22GDN1a8ijxBABOWB9W8MC+h88Roong=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}