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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83ed005f0b4bd6d3726f0f311c13d65db37599513d999275df0aa4e6b016582f' 
  AND token = 'xeP2HitL5iW7UgCq4UmLC/bPNNrVuqNzB4EPY9JnHvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}