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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3011e97076f29a0caccb384bef1ed057150bcffda17a57d8213c443b1cc4e52' 
  AND token = 'JAMH3jCnwkZ71jnibc4d3wLIC5DC1IJT84yRfY+5JFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}