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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961ad45b98643c93963f03f5ffa64e4e032ecda8ee9b9b959337154e6b95f91d' 
  AND token = '+Io87pmCGHpuGKbgZE+qJROu+2GE7TDtJUyb0wG1HDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}