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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fcd476d7a0e73f0494774e5d6710369b3f5a4f5985f3438a3b8915310af270e' 
  AND token = 'weDHjho+fezPwQCMevGxjnht1DpmMexldhwvkdaSaws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}