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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643f783ded2e40a8c1fb556ed5d055b084f04349e75328ded7ff709caf6b5295' 
  AND token = 'X8WhllRWt0PDq7iwlNLSQSyHvn9YovspSLfQ9koFaBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}