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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb0b9c90ef37b65bca58262794aa518d69675e2c8681f6d8d650b0c9a4d2b565' 
  AND token = 'hzT96MsNU9FXIi6C1Z/R6nn+TW4MyVwSRipJMbxng94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}