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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2906c6997b7a4211093a6a420c21f8ae315333e2dcc939b4de7114e514487b0' 
  AND token = 'AxfeXSaVk3ubdGwm8ke6AYYqq1TaGtPENSVQdKltUds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}