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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c12bcd902bb8bd7ceb70f35086f6f300b39dd8fb83da92e1f57df5ed78d9391' 
  AND token = 'pmzIFG3dn7Yqlp6FK+gumrtp/T7v3Fg0P37QPXMqgDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}