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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d8dee946829f4544ea399ba10f20bddf94adefa4e9a65bbd30fdf61e5d728f' 
  AND token = 'D4Ro4iGGStdwn4WrHqtNc+mhBYe6gVPAbGrd5fNPpI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}