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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c501d4fd5019bca1976447a82862ced2cf72622bb611560c04cf99945426b14' 
  AND token = 'Iv27FH6VmZZZ0kOh7sJen5tWgA2xdb3i0UYY57Uubh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}