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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0ed85c847f80ff321108ee2608daa19a8f4aa7959f1e5e5547ae6aad7ff319' 
  AND token = 'EH71OdbsmLUspE+Py2UPr3LqXGQpmASZXzNEZRZESmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}