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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1aa35b0dfa2ae715a245f1db9ff9d5fdca63a9c72ab7fb4294d4abf7c4486c' 
  AND token = 'Iz0D9E7NnTp/wyj8coi/S8ZzkooC21ZrEY4uENJwomk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}