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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcabc5e3f1c3d4cdd34421025d2de04628beb65fe2d3ad7022c9f8f2dc0e9401' 
  AND token = 'mizCOZcRz7rFaVARgFmvN0FJ0dh23HPC+PSOU4Tr4cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}