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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0f1aa24be5ad78f4bded9ddfc52c9266cdbccad08b387751a5113869d59c8f' 
  AND token = 'E725bliWJRGeelGynm8iUmOqPRO9JLl9u1RTR4Kh5ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}