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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27c8e4dade9b64bd5acb3ca27a7fc6ee4910763041cf871e863b4948b4e233c' 
  AND token = 'eAHbhp+rglTsuv430mb9BQO+fi+f5OQBYfGr9ikh7Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}