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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3194c0c283936ec676156cd81c760c4d7364e5c381dfb864b74470a26665b312' 
  AND token = 'TgbyI/NuQoW1rK/sNwWEW5d3rhW/wrWTtoFn+pYrLvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}