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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43b1666844968790357727e809e288e676bd656fae58e2a6d4805ea2d768615' 
  AND token = 'tzZfS0c4Aq0eeT6nNHPn/qAEnfB3/e5KCUjYvyRe4ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}