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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5139ee2006e6d3eca7cd0f3464d6fdb0e01eca0581cc9db1ae556c95c6b1370' 
  AND token = 'GkrdXhvvbPh5PXKA2IufW2K/UdY/6gIYJk/h8ePJzp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}