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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe44c25d32c2a3ba26f94fb045a9eb45af2cbc5b36a1102a0cd8304e8bd46fb' 
  AND token = 'PYF5GHlC3e2kUUAteypk8csBPbDtDwl5baM/jkMjQy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}