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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7acd6b0a89aa66870273e616a81df2cdda6934417c8d339334953ab1a4c48b' 
  AND token = '2dysHIeBQOJFdCRojLyTeShg/qFCAFw616l//BH8PdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}