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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6bb9372d0fb179f82bc5a46a284fe38e090cb67c58b3492f78ed1b6fdebb589' 
  AND token = 'L6GinoW6oOGPX0afoE/YVzOtQ/HTwwiz2HUFyY58ZqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}