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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa6749e3489c4b7ecccc7201f114a2fddca4a908f48290401fde38dcc36b45c6' 
  AND token = 'z0ZiGCUW1mZuYUURrVy5EnifQdNYMywyVgjLPLWv1ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}