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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0176ff0994fa63b6344ccaf553b5f4fb0a46372215da6db057129da92f7403' 
  AND token = 'iC3OtDhZ7a7JDayhP6jOa/pUb5dKuFxpL4F4byTb9Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}