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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dad75b2596d3580b194dd8d533230168b5f4487a664f0fc5634f94c61fbf46a1' 
  AND token = 'EgDE45+DxwK1J+x0tmrH2aRKwUooF6TkN1BuK2TnmIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}