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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3da4b34794bd919fb8245a8226a3dfd58da80b4334aba89a01835738a43e30' 
  AND token = 'mnuWPDCPq+DG8Sfp//hrLLk8/iAX/rqK3LWGakC0zq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}