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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316611ddeac66ae602e3e587c110c49ff8c69d331bffda4ca7c62484c1d31066' 
  AND token = 'BY2ysOJ1iOdW2AdqAh+ClrxuzRCpKYW6yL0r+D4MzA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}