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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e12ba50a1e65f0fcf1444f90a124a86701bb9ab8a7b24b367f235106e3e480b' 
  AND token = 'eA6BdpxFBI/Een13+0rzLpLtcB3Sp7RaAb9Vaa8GAus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}