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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb1d608da0c222c4c1265a20f3eba37babcbaa0fd91b667fa31e47f1a3d80cb' 
  AND token = 'lxfDg8tA/CkrnZY/9MrN952BeeNDUwhPk2W3/WYzch0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}