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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1fc51957c0f22df9bb19584847d077bfdb0e455be2d3f5464c61fed4e43d535' 
  AND token = 'NpojWl0W8UG68+zxqg8wWjoDbaMjTtOgBuFAI4ORfT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}