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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60e4f1e17db080713a967c95bdffdf686cc5e2f1717db0c93df788c56a54881' 
  AND token = '0S183p/ls4ccTiXOExHDYv+5TXvihn+6RHhiVGQJuqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}