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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5eb1161f99f4d92b045bf9859f9018be8b64740840d538ccb47c25690d85f2' 
  AND token = 'j2afg9R0WztwhT6vWT4T9cSkf53fpN0qyMRQgXmrSBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}