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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0fb846c3ef74e65690c15cee99f8324920a11dd991631b7b0755c6638e2e2fd' 
  AND token = 'ZRLsEuQnZ1Cw/gy4r9Pm8RTFmmzdiWHO8a/IvInRGqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}