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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a70307a35ab2e294c489ca5308eb5e75dd3522416357198c95b38027dac1c5' 
  AND token = 'ZBG1k3N9vT8Qev57olk6EZOd9s5zrvyuDaVBVB6IqX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}