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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a68012a126cc9a243316f1f298b2f91bf4a2a22112726cba257f37a73812bf8' 
  AND token = 'yr0L+wIg+C9WvA/tzsli/ANhmI+ewTSAd1lwrlvUWMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}