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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0b4d8f6b27b4b0991f7d89cb5fdbc7fdaed28c2fe29216349767d72699757cf' 
  AND token = 'M9ZzdI8IhWLeiR33o+aj8cyVhni3TmOvMTiODmNZ0ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}