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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d1ae2e88240d6ec47ce420df09138d7c60355b47cc533863c9555c456e76e1' 
  AND token = 'kWmYcjfUChVwyCTelvFg4uIoWUpV6HECcNtKFg9fthQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}