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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6151c0151350ce25b586f25a74b8e80c2986c8fc445cbebdd9ee5b4f18ae78b6' 
  AND token = 'ZS22I9VqF00LmV2VISiBhgv61EC4KGo35n6YKSna/XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}